KANNA
SCELETIUM TORTUOSUM
Sceletium’s mood-elevating action is caused by a number of alkaloids including Mesembrine, Mesembrenol and Mesembrenone which interact with the brain's dopamine and serotonin receptors. These major alkaloids present in Sceletium have been demonstrated to work as a serotonin reuptake inhibitor.
More Information and References
Sceletium tortuosum VIEW
Acute Effects of Sceletium tortuosum VIEW
NAD+
NAD is a coenzyme found in all living cells that can optimize your body’s cellular energy and mitochondrial production. It is used both for its antioxidant effect (slowing down the aging process) and to improve mental clarity, alertness and concentration.
A Distinctive Feature of NAD Homeostasis*
NAD+ is not merely a redox cofactor. It is also a key signalling molecule that controls cell function and survival in response to environmental changes such as nutrient intake and cellular damage. Fluctuations in NAD impact mitochondrial function and metabolism, redox reactions, circadian rhythm, immune response and inflammation, DNA repair, cell division, protein - protein signaling, chromatin and epigenetics.
*Maintaining a relatively stable internal state despite changes in one’s environment.
More Information and References
Therapeutic potential of NAD-boosting molecules VIEW
Implications of altered NAD metabolism in metabolic disorders VIEW
Vit B6
Vitamin B6 helps the body produce the hormones serotonin (which regulates mood) and norepinephrine (which helps your body cope with stress). Melatonin production is also increased by intake of Vitamin B6, which is important for regulating your natural sleep cycle.
More Information and References
Penn State Health Milton S. Hershey Medical Center: Vitamin B6 (Pyridoxine) VIEW
B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review VIEW
